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Information about Orlistat.

Kidney problemslittle or no urinatingswelling in your feet or anklesfeeling tired or short of breathor.

Orlistat is a reversible inhibitor of gastrointestinal lipasesIt exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipasesThe inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglyceridesAs undigested triglycerides are not absorbedthe resulting caloric deficit may have a positive effect on weight control.

Orlistat is a white to off-white crystalline powderOrlistat is practically insoluble in waterfreely soluble in chloroformand very soluble in methanol and ethanolOrlistat has no pK within the physiological pH range.

This medication is sometimes prescribed for other usesask your doctor or pharmacist for more information.

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orlistat is sold as xenical in a prescription-strength formulation, and as alli in the otc form.

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